Nef-Mediated Downregulation of CD4 Enhances Human Immunodeficiency Virus Type 1 Replication in Primary T Lymphocytes

The accessory protein Nef plays a crucial role in primate lentivirus pathogenesis. Nef enhances human immunodeficiency virus type 1 (HIV-1) infectivity in culture and stimulates viral replication in primary T cells. In this study, we investigated the relationship between HIV-1 replication efficiency...

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Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Lundquist, Christopher A., Tobiume, Minoru, Zhou, Jing, Unutmaz, Derya, Aiken, Christopher
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Replication
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11932428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.9.4625-4633.2002
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