Surfactant proteins A and D inhibit the growth of Gram-negative bacteria by increasing membrane permeability

The pulmonary collectins, surfactant proteins A (SP-A) and D (SP-D), have been reported to bind lipopolysaccharide (LPS), opsonize microorganisms, and enhance the clearance of lung pathogens. In this study, we examined the effect of SP-A and SP-D on the growth and viability of Gram-negative bacteria...

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Detalhes bibliográficos
Main Authors: Wu, Huixing, Kuzmenko, Alexander, Wan, Sijue, Schaffer, Lyndsay, Weiss, Alison, Fisher, James H., Kim, Kwang Sik, McCormack, Francis X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155045/
https://ncbi.nlm.nih.gov/pubmed/12750409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316889
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