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GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor–stimulated muscle glucose utilization

Recent evidence suggests the existence of a hepatoportal vein glucose sensor, whose activation leads to enhanced glucose use in skeletal muscle, heart, and brown adipose tissue. The mechanism leading to this increase in whole body glucose clearance is not known, but previous data suggest that it is...

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Autors principals: Burcelin, Rémy, Crivelli, Valerie, Perrin, Christophe, Costa, Anabela Da, Mu, James, Kahn, Barbara B., Birnbaum, Morris J., Kahn, C. Ronald, Vollenweider, Peter, Thorens, Bernard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155044/
https://ncbi.nlm.nih.gov/pubmed/12750405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316888
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