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GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor–stimulated muscle glucose utilization

Recent evidence suggests the existence of a hepatoportal vein glucose sensor, whose activation leads to enhanced glucose use in skeletal muscle, heart, and brown adipose tissue. The mechanism leading to this increase in whole body glucose clearance is not known, but previous data suggest that it is...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphov: Burcelin, Rémy, Crivelli, Valerie, Perrin, Christophe, Costa, Anabela Da, Mu, James, Kahn, Barbara B., Birnbaum, Morris J., Kahn, C. Ronald, Vollenweider, Peter, Thorens, Bernard
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12750405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16888
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