Heterozygous deficiency of hypoxia-inducible factor–2α protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia

Chronic hypoxia induces pulmonary vascular remodeling, leading to pulmonary hypertension, right ventricular hypertrophy, and heart failure. Heterozygous deficiency of hypoxia-inducible factor–1α (HIF-1α), which mediates the cellular response to hypoxia by increasing expression of genes involved in e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brusselmans, Koen, Compernolle, Veerle, Tjwa, Marc, Wiesener, Michael S., Maxwell, Patrick H., Collen, Désiré, Carmeliet, Peter
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2003
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC155039/
https://ncbi.nlm.nih.gov/pubmed/12750401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200315496
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak