Gene Expression Profiling of the Cellular Transcriptional Network Regulated by Alpha/Beta Interferon and Its Partial Attenuation by the Hepatitis C Virus Nonstructural 5A Protein

Alpha/beta interferons (IFN-α/β) induce potent antiviral and antiproliferative responses and are used to treat a wide range of human diseases, including chronic hepatitis C virus (HCV) infection. However, for reasons that remain poorly understood, many HCV isolates are resistant to IFN therapy. To b...

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Vydáno v:	J Virol
Hlavní autoři:	Geiss, Gary K., Carter, Victoria S., He, Yupeng, Kwieciszewski, Bartlomiej K., Holzman, Ted, Korth, Marcus J., Lazaro, Catherine A., Fausto, Nelson, Bumgarner, Roger E., Katze, Michael G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Virus-Cell Interactions
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12743294/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.11.6367-6375.2003
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