Gene Expression Profiling of the Cellular Transcriptional Network Regulated by Alpha/Beta Interferon and Its Partial Attenuation by the Hepatitis C Virus Nonstructural 5A Protein

Alpha/beta interferons (IFN-α/β) induce potent antiviral and antiproliferative responses and are used to treat a wide range of human diseases, including chronic hepatitis C virus (HCV) infection. However, for reasons that remain poorly understood, many HCV isolates are resistant to IFN therapy. To b...

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Detalhes bibliográficos
Main Authors: Geiss, Gary K., Carter, Victoria S., He, Yupeng, Kwieciszewski, Bartlomiej K., Holzman, Ted, Korth, Marcus J., Lazaro, Catherine A., Fausto, Nelson, Bumgarner, Roger E., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC155033/
https://ncbi.nlm.nih.gov/pubmed/12743294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6367-6375.2003
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