Ras-Mediated Suppression of TGFβRII Expression in Intestinal Epithelial Cells Involves Raf-Independent Signaling

Ras-transformed intestinal epithelial cells are resistant to the growth inhibitory actions of TGFβ and have a marked decrease in expression of the TGFβ type II receptor (TGFβRII). Rat intestinal epithelial cells (RIE) were stably transfected with activated Ras, Sos and Raf constructs and tested for...

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Autores principales: Bulus, Nada M, Sheng, Hong-Miao, Sizemore, Nywanna, Oldham, Sean M, Barnett, Joey V, Coffey, Robert J, Beauchamp, Daniel R, Barnard, John A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature America, Inc. 2000
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550294/
https://ncbi.nlm.nih.gov/pubmed/11005570
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