KIR/HLA Pleiotropism: Protection against Both HIV and Opportunistic Infections

The compound genotype KIR3DS1/HLA-B Bw4-80I, which presumably favors natural killer cell activation, has been implicated in protection against HIV disease. We show that this genotype confers dual protection over the course of HIV disease; early direct containment of HIV viral load, and late specific...

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Detalhes bibliográficos
Main Authors: Qi, Ying, Martin, Maureen P, Gao, Xiaojiang, Jacobson, Lisa, Goedert, James J, Buchbinder, Susan, Kirk, Gregory D, O'Brien, Stephen J, Trowsdale, John, Carrington, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550271/
https://ncbi.nlm.nih.gov/pubmed/16933987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020079
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