Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1

Allotypes of the natural killer (NK) cell receptor KIR3DL1 vary in both NK cell expression patterns and inhibitory capacity upon binding to their ligands, HLA-B Bw4 molecules, present on target cells. Using a sample size of over 1,500 human immunodeficiency virus (HIV)(+) individuals, we show that v...

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Autors principals: Martin, Maureen P, Qi, Ying, Gao, Xiaojiang, Yamada, Eriko, Martin, Jeffrey N, Pereyra, Florencia, Colombo, Sara, Brown, Elizabeth E, Shupert, W Lesley, Phair, John, Goedert, James J, Buchbinder, Susan, Kirk, Gregory D, Telenti, Amalio, Connors, Mark, O’Brien, Stephen J, Walker, Bruce D, Parham, Peter, Deeks, Steven G, McVicar, Daniel W, Carrington, Mary
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135476/
https://ncbi.nlm.nih.gov/pubmed/17496894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng2035
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