Optimization of the helper-dependent adenovirus system for production and potency in vivo

Helper-dependent (HD) adenoviral vectors devoid of all viral coding sequences provide for safe and highly efficient gene transfer with long-lasting transgene expression. High titer stocks of HD vectors can be generated by using the cre-recombinase system. However, we have encountered difficulties wi...

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Библиографические подробности
Главные авторы: Sandig, Volker, Youil, Rima, Bett, Andrew J., Franlin, Laura L., Oshima, Masanobu, Maione, Domenico, Wang, Fubao, Metzker, Michael L., Savino, Rocco, Caskey, C. Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2000
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC15501/
https://ncbi.nlm.nih.gov/pubmed/10655474
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