Identification of Herpes Simplex Virus Type 1 Latency-Associated Transcript Sequences That both Inhibit Apoptosis and Enhance the Spontaneous Reactivation Phenotype

The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) gene is essential for the high spontaneous and induced reactivation phenotype of HSV-1 in the rabbit ocular model and for the high induced reactivation phenotype in the mouse ocular model. Recently we showed that LAT has an...

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Autores principales: Jin, Ling, Peng, Weiping, Perng, Guey-Chuen, Brick, David J., Nesburn, Anthony B., Jones, Clinton, Wechsler, Steven L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC155006/
https://ncbi.nlm.nih.gov/pubmed/12743314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6556-6561.2003
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