The charged region of Hsp90 modulates the function of the N-terminal domain

Hsp90, an abundant heat shock protein that is highly expressed even under physiological conditions, is involved in the folding of key molecules of the cellular signal transduction system such as kinases and steroid receptors. It seems to contain two chaperone sites differing in substrate specificity...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Scheibel, Thomas, Siegmund, Heiko Ingo, Jaenicke, Rainer, Ganz, Peter, Lilie, Hauke, Buchner, Johannes
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1999
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15457/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1297
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