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Cyclin D1 and mammary carcinoma: new insights from transgenic mouse models
Cyclin D1 is one of the most commonly overexpressed oncogenes in breast cancer, with 45–50% of primary ductal carcinomas overexpressing this oncoprotein. Targeted deletion of the gene encoding cyclin D1 demonstrates an essential role in normal mammary gland development while transgenic studies provi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC154565/ https://ncbi.nlm.nih.gov/pubmed/11879554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr411 |
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