Regulation of T cell activation and tolerance by PDL2

T cell activation and tolerance are regulated by costimulatory molecules. Although PD-1 serves as a crucial negative regulator of T cells, the function of its ligands, PDL1 and PDL2, is still controversial. In this study, we created a PDL2-deficient mouse to characterize its function in T cell activ...

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Hlavní autoři: Zhang, Yongliang, Chung, Yeonseok, Bishop, Caroline, Daugherty, Betsy, Chute, Hilary, Holst, Paige, Kurahara, Carole, Lott, Fred, Sun, Ning, Welcher, Andrew A., Dong, Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544232/
https://ncbi.nlm.nih.gov/pubmed/16864790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601347103
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