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Co-administration of CD40 agonistic antibody and antigen fails to overcome the induction of oral tolerance
T-cell stimulation in the absence of a second, costimulatory signal can lead to anergy or deletion. There is growing evidence that peripheral tolerance to an exogenous antigen might be caused by the lack of costimulatory molecules on antigen-presenting cells (APCs). In the present study, we examined...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782393/ https://ncbi.nlm.nih.gov/pubmed/14678195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2003.01787.x |
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