Collagen-induced arthritis is exacerbated in IL-10-deficient mice

IL-10 is a potent immunoregulatory cytokine attenuating a wide range of immune effector and inflammatory responses. In the present study, we assess whether endogenous levels of IL-10 function to regulate the incidence and severity of collagen-induced arthritis. DBA/1 wildtype (WT), heterozygous (IL-...

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Autori principali: Finnegan, Alison, Kaplan, Charles D, Cao, Yanxia, Eibel, Hermann, Glant, Tibor T, Zhang, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2003
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC154422/
https://ncbi.nlm.nih.gov/pubmed/12716449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar601
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