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Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells

It was, until now, not entirely clear how the nervous system attains its cellular phenotypic diversity and wired complexity during development. Here we describe how environmental interactions alone can modify the development of neurogenic precursor cells. Upon evaluating distinct growth-permissive s...

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Hlavní autoři: Goetz, A. Katrin, Scheffler, Bjorn, Chen, Huan-Xin, Wang, Shanshan, Suslov, Oleg, Xiang, Hui, Brüstle, Oliver, Roper, Steve N., Steindler, Dennis A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544174/
https://ncbi.nlm.nih.gov/pubmed/16832065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0510926103
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