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PCR inhibition by reverse transcriptase leads to an overestimation of amplification efficiency

This study addresses the problem of PCR inhibition by reverse transcriptase. It has been shown that the inhibition occurs mostly when a small amount of RNA is taken for RT reaction, and it is more visible for rarely expressed transcripts. We show here that the inhibition takes place regardless of wh...

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Bibliographic Details
Main Authors: Suslov, Oleg, Steindler, Dennis A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1298932/
https://ncbi.nlm.nih.gov/pubmed/16314311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni176
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