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Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage

Acid-sensitive ion channels (ASICs) are proton-gated and belong to the family of degenerin channels. In the mammalian nervous system, ASICs are most well known in sensory neurons, where they are involved in nociception, occurring when injury or inflammation causes acidification. ASICs also are widel...

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Autors principals: Pidoplichko, Volodymyr I., Dani, John A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544094/
https://ncbi.nlm.nih.gov/pubmed/16847263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600768103
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