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Dilated Perivascular Space in the Midbrain May Reflect Dopamine Neuronal Degeneration in Parkinson’s Disease

Background: The imbalance between the production and clearance of alpha-synuclein and its consequent accumulation plays a pivotal role in the pathogenesis of Parkinson’s disease (PD). The diminished clearance of alpha-synuclein may be partly attributable to impaired interstitial fluid, which can be...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Li, Yanxuan, Zhu, Zili, Chen, Jie, Zhang, Minming, Yang, Yunjun, Huang, Peiyu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289975/
https://ncbi.nlm.nih.gov/pubmed/32581771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2020.00161
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