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Consequences of receptor editing at the λ locus: Multireactivity and light chain secretion
To investigate the manner in which B cells with λ light (L) chains undergo receptor editing, we have studied hybridoma panels from 56R/κ-deleted (kdel) mice. 56R/kdel mice only produce four L chains (λ1, λ2, λ3, and λX). They also have a simplified heavy (H) chain repertoire: All B cells start out w...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544076/ https://ncbi.nlm.nih.gov/pubmed/16847259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604053103 |
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