Consequences of receptor editing at the λ locus: Multireactivity and light chain secretion

To investigate the manner in which B cells with λ light (L) chains undergo receptor editing, we have studied hybridoma panels from 56R/κ-deleted (kdel) mice. 56R/kdel mice only produce four L chains (λ1, λ2, λ3, and λX). They also have a simplified heavy (H) chain repertoire: All B cells start out w...

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Detaylı Bibliyografya
Asıl Yazarlar: Doyle, Colleen M., Han, Jiong, Weigert, Martin G., Prak, Eline T. Luning
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2006
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544076/
https://ncbi.nlm.nih.gov/pubmed/16847259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604053103
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