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Biophysical model of self-organized spindle formation patterns without centrosomes and kinetochores

Eukaryotic cell division and chromosome segregation depend crucially on the mitotic spindle pattern formation. The usual pathway for spindle production involves microtubule polymerization from two centrosomes. However, experiments using Xenopus extracts with micrometer-sized chromatin-coated beads f...

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Main Authors: Schaffner, Stuart C., José, Jorge V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544059/
https://ncbi.nlm.nih.gov/pubmed/16844776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604721103
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