Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly

In animal somatic cells, bipolar spindle formation requires separation of the centrosome-based spindle poles. Centrosome separation relies on multiple pathways, including cortical forces and antiparallel microtubule (MT) sliding, which are two activities controlled by the protein kinase aurora A. We...

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Main Authors: Toso, Alberto, Winter, Jennifer R., Garrod, Ainslie J., Amaro, Ana C., Meraldi, Patrick, McAinsh, Andrew D.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2009
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646558/
https://ncbi.nlm.nih.gov/pubmed/19204145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809055
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