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Biophysical model of self-organized spindle formation patterns without centrosomes and kinetochores

Eukaryotic cell division and chromosome segregation depend crucially on the mitotic spindle pattern formation. The usual pathway for spindle production involves microtubule polymerization from two centrosomes. However, experiments using Xenopus extracts with micrometer-sized chromatin-coated beads f...

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Detalhes bibliográficos
Main Authors: Schaffner, Stuart C., José, Jorge V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544059/
https://ncbi.nlm.nih.gov/pubmed/16844776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604721103
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