Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

Parkinson's disease (PD) is a neurodegenerative disorder of uncertain pathogenesis characterized by the loss of the nigrostriatal dopaminergic neurons, which can be modeled by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Increased expression of cyclooxygenase type 2 (COX-2) an...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Teismann, Peter, Tieu, Kim, Choi, Dong-Kug, Wu, Du-Chu, Naini, Ali, Hunot, Stéphane, Vila, Miquel, Jackson-Lewis, Vernice, Przedborski, Serge
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2003
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12702778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0837397100
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