Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

Parkinson's disease (PD) is a neurodegenerative disorder of uncertain pathogenesis characterized by the loss of the nigrostriatal dopaminergic neurons, which can be modeled by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Increased expression of cyclooxygenase type 2 (COX-...

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Bibliografiske detaljer
Main Authors: Teismann, Peter, Tieu, Kim, Choi, Dong-Kug, Wu, Du-Chu, Naini, Ali, Hunot, Stéphane, Vila, Miquel, Jackson-Lewis, Vernice, Przedborski, Serge
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154369/
https://ncbi.nlm.nih.gov/pubmed/12702778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0837397100
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