Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

The control of lipid and glucose metabolism is closely linked. The nuclear receptors liver X receptor (LXR)α and LXRβ have been implicated in gene expression linked to lipid homeostasis; however, their role in glucose metabolism is not clear. We demonstrate here that the synthetic LXR agonist GW3965...

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Autores principales: Laffitte, Bryan A., Chao, Lily C., Li, Jing, Walczak, Robert, Hummasti, Sarah, Joseph, Sean B., Castrillo, Antonio, Wilpitz, Damien C., Mangelsdorf, David J., Collins, Jon L., Saez, Enrique, Tontonoz, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2003
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC154360/
https://ncbi.nlm.nih.gov/pubmed/12697904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0830671100
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