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Chemically programmed monoclonal antibodies for cancer therapy: Adaptor immunotherapy based on a covalent antibody catalyst

Proposing that a blend of the chemical diversity of small synthetic molecules with the immunological characteristics of the antibody molecule will lead to therapeutic agents with superior properties, we here present a device that equips small synthetic molecules with both effector function and long...

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Detalles Bibliográficos
Autores principales: Rader, Christoph, Sinha, Subhash C., Popkov, Mikhail, Lerner, Richard A., Barbas, Carlos F.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC154356/
https://ncbi.nlm.nih.gov/pubmed/12702756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0931308100
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