Acidic pH induces topoisomerase II-mediated DNA damage
Acidic pH plays an important role in various pathophysiological states and has been demonstrated to be carcinogenic in animal models. Recent studies have also implicated acidic pH in the development of preneoplastic Barrett's esophagus in human. However, little is known about the molecular mechanism...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154323/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12692309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0935978100 |
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