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The prolyl isomerase Pin1 in breast development and cancer

The prolyl isomerase Pin1 specifically isomerizes certain phosphorylated Ser/Thr-Pro bonds and thereby regulates various cellular processes. Pin1 is a target of several oncogenic pathways and is overexpressed in human breast cancer. Its overexpression can lead to upregulation of cyclin D1 and transf...

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Bibliografiske detaljer
Main Authors: Wulf, Gerburg, Ryo, Akihide, Liou, Yih-Cherng, Lu, Kun Ping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154150/
https://ncbi.nlm.nih.gov/pubmed/12631385
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