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The role of the ubiquitination-proteasome pathway in breast cancer: Applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer

The ubiquitin-proteasome pathway is responsible for most eukaryotic intracellular protein degradation. This pathway has been validated as a target for antineoplastic therapy using both in vitro and preclinical models of human malignancies, and is influenced as part of the mechanism of action of cert...

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Detalhes bibliográficos
Main Authors: Orlowski, Robert Z, Dees, E Claire
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154126/
https://ncbi.nlm.nih.gov/pubmed/12559038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr460
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