Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

Studies of naturally occurring polymorphisms of the CCR5 gene have shown that deletion of the functional receptor or reduced expression of the gene can have beneficial effects in preventing HIV-1 infection or delaying disease. Because these polymorphisms are found in otherwise healthy people, strate...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Steinberger, Peter, Andris-Widhopf, Jennifer, Bühler, Bernd, Torbett, Bruce E., Barbas, Carlos F.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2000
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15412/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639161/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.805
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