Roles of DegP in Prevention of Protein Misfolding in the Periplasm upon Overexpression of Penicillin Acylase in Escherichia coli

Enhancement of the production of soluble recombinant penicillin acylase in Escherichia coli via coexpression of a periplasmic protease/chaperone, DegP, was demonstrated. Coexpression of DegP resulted in a shift of in vivo penicillin acylase (PAC) synthesis flux from the nonproductive pathway to the...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Pan, Kao-Lu, Hsiao, Hsu-Chou, Weng, Chiao-Ling, Wu, Ming-Sheng, Chou, C. Perry
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.3020-3030.2003
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