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Roles of DegP in Prevention of Protein Misfolding in the Periplasm upon Overexpression of Penicillin Acylase in Escherichia coli

Enhancement of the production of soluble recombinant penicillin acylase in Escherichia coli via coexpression of a periplasmic protease/chaperone, DegP, was demonstrated. Coexpression of DegP resulted in a shift of in vivo penicillin acylase (PAC) synthesis flux from the nonproductive pathway to the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Bacteriol
Prif Awduron: Pan, Kao-Lu, Hsiao, Hsu-Chou, Weng, Chiao-Ling, Wu, Ming-Sheng, Chou, C. Perry
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730160/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.3020-3030.2003
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