Roles of DegP in Prevention of Protein Misfolding in the Periplasm upon Overexpression of Penicillin Acylase in Escherichia coli

Enhancement of the production of soluble recombinant penicillin acylase in Escherichia coli via coexpression of a periplasmic protease/chaperone, DegP, was demonstrated. Coexpression of DegP resulted in a shift of in vivo penicillin acylase (PAC) synthesis flux from the nonproductive pathway to the...

詳細記述

書誌詳細

出版年:	J Bacteriol
主要な著者:	Pan, Kao-Lu, Hsiao, Hsu-Chou, Weng, Chiao-Ling, Wu, Ming-Sheng, Chou, C. Perry
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 2003
主題:	Genetics and Molecular Biology
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730160/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.3020-3030.2003
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