The yggH Gene of Escherichia coli Encodes a tRNA (m(7)G46) Methyltransferase

We cloned, expressed, and purified the Escherichia coli YggH protein and show that it catalyzes the S-adenosyl-l-methionine-dependent formation of N(7)-methylguanosine at position 46 (m(7)G46) in tRNA. Additionally, we generated an E. coli strain with a disrupted yggH gene and show that the mutant s...

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Bibliographic Details

Published in:	J Bacteriol
Main Authors:	De Bie, Lara G. S., Roovers, Martine, Oudjama, Yamina, Wattiez, Ruddy, Tricot, Catherine, Stalon, Victor, Droogmans, Louis, Bujnicki, Janusz M.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2003
Subjects:	Genetics and Molecular Biology
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154064/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12730187/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.10.3238-3243.2003
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