Cloning and characterization of tRNA (m(1)A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures

N(1)-methyladenosine (m(1)A) is found at position 58 in the T-loop of many tRNAs. In yeast, the formation of this modified nucleoside is catalyzed by the essential tRNA (m(1)A58) methyltransferase, a tetrameric enzyme that is composed of two types of subunits (Gcd14p and Gcd10p). In this report we d...

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Asıl Yazarlar: Droogmans, Louis, Roovers, Martine, Bujnicki, Janusz M., Tricot, Catherine, Hartsch, Thomas, Stalon, Victor, Grosjean, Henri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2003
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC153742/
https://ncbi.nlm.nih.gov/pubmed/12682365
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