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Prevention of passively transferred experimental autoimmune myasthenia gravis by a phage library-derived cyclic peptide

Many pathogenic antibodies in myasthenia gravis (MG) and its animal model, experimental autoimmune MG (EAMG), are directed against the main immunogenic region (MIR) of the acetylcholine receptor (AcChoR). These antibodies are highly conformation dependent; hence, linear peptides derived from native...

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Main Authors: Venkatesh, Natarajan, Im, Sin-Heyog, Balass, Moshe, Fuchs, Sara, Katchalski-Katzir, Ephraim
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC15404/
https://ncbi.nlm.nih.gov/pubmed/10639153
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