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Mutations in the N-Terminal Region of Influenza Virus PB2 Protein Affect Virus RNA Replication but Not Transcription

PB2 mutants of influenza virus were prepared by altering conserved positions in the N-terminal region of the protein that aligned with the amino acids of the eIF4E protein, involved in cap recognition. These mutant genes were used to reconstitute in vivo viral ribonucleoproteins (RNPs) whose biologi...

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Detalhes bibliográficos
Main Authors: Gastaminza, Pablo, Perales, Beatriz, Falcón, Ana M., Ortín, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153989/
https://ncbi.nlm.nih.gov/pubmed/12692212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5098-5108.2003
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