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Analysis of the Mechanism by Which the Small-Molecule CCR5 Antagonists SCH-351125 and SCH-350581 Inhibit Human Immunodeficiency Virus Type 1 Entry

Human immunodeficiency virus type 1 (HIV-1) entry is mediated by the consecutive interaction of the envelope glycoprotein gp120 with CD4 and a coreceptor such as CCR5 or CXCR4. The CCR5 coreceptor is used by the most commonly transmitted HIV-1 strains that often persist throughout the course of infe...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Virol
Principais autores: Tsamis, Fotini, Gavrilov, Svetlana, Kajumo, Francis, Seibert, Christoph, Kuhmann, Shawn, Ketas, Tom, Trkola, Alexandra, Palani, Anadan, Clader, John W., Tagat, Jayaram R., McCombie, Stuart, Baroudy, Bahige, Moore, John P., Sakmar, Thomas P., Dragic, Tatjana
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2003
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153966/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12692222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.9.5201-5208.2003
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