Rapid Tumor Formation of Human T-Cell Leukemia Virus Type 1-Infected Cell Lines in Novel NOD-SCID/γc(null) Mice: Suppression by an Inhibitor against NF-κB

We established a novel experimental model for human T-cell leukemia virus type 1 (HTLV-1)-induced tumor using NOD-SCID/γc(null) (NOG) mice. This model is very useful for investigating the mechanism of tumorigenesis and malignant cell growth of adult T-cell leukemia (ATL)/lymphoma, which still remain...

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Detalhes bibliográficos
Main Authors: Dewan, M. Zahidunnabi, Terashima, Kazuo, Taruishi, Midori, Hasegawa, Hideki, Ito, Mamoru, Tanaka, Yuetsu, Mori, Naoki, Sata, Tetsutaro, Koyanagi, Yoshio, Maeda, Michiyuki, Kubuki, Yoko, Okayama, Akihiko, Fujii, Masahiro, Yamamoto, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153944/
https://ncbi.nlm.nih.gov/pubmed/12692230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5286-5294.2003
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