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Humanized NOD/SCID/IL2Rγ(null) Mice Transplanted with Hematopoietic Stem Cells under Nonmyeloablative Conditions Show Prolonged Life Spans and Allow Detailed Analysis of Human Immunodeficiency Virus Type 1 Pathogenesis
In a previous study, we demonstrated that humanized NOD/SCID/IL2Rγ(null) (hNOG) mice constructed with human hematopoietic stem cells (HSCs) allow efficient human immunodeficiency virus type 1 (HIV-1) infection. However, HIV-1 infection could be monitored for only 43 days in the animals due to their...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2169100/ https://ncbi.nlm.nih.gov/pubmed/17881441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01353-07 |
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