Human Neutralizing Fab Molecules against Severe Acute Respiratory Syndrome Coronavirus Generated by Phage Display

Human recombinant Fab fragments specific for the spike protein of severe acute respiratory syndrome coronavirus (SARS-CoV) were screened from a human Fab library, which was generated from RNAs from peripheral lymphocytes of convalescent SARS patients. Among 50 randomly picked clones, 12 Fabs special...

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Detalhes bibliográficos
Main Authors: Kang, Xiaoping, Yang, Bao-an, Hu, Yuyang, Zhao, Hui, Xiong, Wei, Yang, Yinhui, Si, Bingyin, Zhu, Qingyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Cellular Immunology, Antibodies, and Mediators of Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1539127/
https://ncbi.nlm.nih.gov/pubmed/16893997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00037-06
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