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Physicochemical Properties That Enhance Discriminative Antibacterial Activity of Short Dermaseptin Derivatives

Antimicrobial peptides are widely believed to exert their effects by nonspecific mechanisms. We assessed the extent to which physicochemical properties can be exploited to promote discriminative activity by manipulating the N-terminal sequence of the 13-mer dermaseptin derivative K(4)-S4(1-13) (P)....

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Detalhes bibliográficos
Main Authors: Rotem, Shahar, Radzishevsky, Inna, Mor, Amram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538664/
https://ncbi.nlm.nih.gov/pubmed/16870756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00030-06
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