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Effects of Acyl versus Aminoacyl Conjugation on the Properties of Antimicrobial Peptides

To investigate the importance of increased hydrophobicity at the amino end of antimicrobial peptides, a dermaseptin derivative was used as a template for a systematic acylation study. Through a gradual increase of the acyl moiety chain length, hydrophobicity was monitored and further modulated by ac...

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Detalhes bibliográficos
Main Authors: Radzishevsky, Inna S., Rotem, Shahar, Zaknoon, Fadia, Gaidukov, Leonid, Dagan, Arie, Mor, Amram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140510/
https://ncbi.nlm.nih.gov/pubmed/15917541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.6.2412-2420.2005
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