Population Genetics Study of Isoniazid Resistance Mutations and Evolution of Multidrug-Resistant Mycobacterium tuberculosis

The molecular basis for isoniazid resistance in Mycobacterium tuberculosis is complex. Putative isoniazid resistance mutations have been identified in katG, ahpC, inhA, kasA, and ndh. However, small sample sizes and related potential biases in sample selection have precluded the development of stati...

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Autors principals: Hazbón, Manzour Hernando, Brimacombe, Michael, Bobadilla del Valle, Miriam, Cavatore, Magali, Guerrero, Marta Inírida, Varma-Basil, Mandira, Billman-Jacobe, Helen, Lavender, Caroline, Fyfe, Janet, García-García, Lourdes, León, Clara Inés, Bose, Mridula, Chaves, Fernando, Murray, Megan, Eisenach, Kathleen D., Sifuentes-Osornio, José, Cave, M. Donald, Ponce de León, Alfredo, Alland, David
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538650/
https://ncbi.nlm.nih.gov/pubmed/16870753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00112-06
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