Population Genetics Study of Isoniazid Resistance Mutations and Evolution of Multidrug-Resistant Mycobacterium tuberculosis

The molecular basis for isoniazid resistance in Mycobacterium tuberculosis is complex. Putative isoniazid resistance mutations have been identified in katG, ahpC, inhA, kasA, and ndh. However, small sample sizes and related potential biases in sample selection have precluded the development of stati...

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Détails bibliographiques
Auteurs principaux: Hazbón, Manzour Hernando, Brimacombe, Michael, Bobadilla del Valle, Miriam, Cavatore, Magali, Guerrero, Marta Inírida, Varma-Basil, Mandira, Billman-Jacobe, Helen, Lavender, Caroline, Fyfe, Janet, García-García, Lourdes, León, Clara Inés, Bose, Mridula, Chaves, Fernando, Murray, Megan, Eisenach, Kathleen D., Sifuentes-Osornio, José, Cave, M. Donald, Ponce de León, Alfredo, Alland, David
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Mechanisms of Resistance
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538650/
https://ncbi.nlm.nih.gov/pubmed/16870753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00112-06
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