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Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant Rat P2X(3) receptor

Synthetic 21-bp-long short interfering RNAs (siRNA) can stimulate sequence-specific mRNA degradation in mammalian cell cultures, a process referred to as RNA interference (RNAi). In the present study, the potential of RNAi was compared to the traditional antisense approach, acting mainly via RnaseH,...

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Библиографические подробности
Главные авторы: Hemmings-Mieszczak, Maja, Dorn, Gabriele, Natt, François J., Hall, Jonathan, Wishart, William L.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2003
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC153750/
https://ncbi.nlm.nih.gov/pubmed/12682362
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