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Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant Rat P2X(3) receptor

Synthetic 21-bp-long short interfering RNAs (siRNA) can stimulate sequence-specific mRNA degradation in mammalian cell cultures, a process referred to as RNA interference (RNAi). In the present study, the potential of RNAi was compared to the traditional antisense approach, acting mainly via RnaseH,...

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Udgivet i:Nucleic Acids Res
Principais autores: Hemmings-Mieszczak, Maja, Dorn, Gabriele, Natt, François J., Hall, Jonathan, Wishart, William L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153750/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12682362/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg322
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